Dr. Jamie Rothenburger is a veterinarian and scientist whose research has made valuable and unique contributions to the understanding of veterinary medicine and wildlife diseases. She has published over 20 peer-reviewed papers, 16 of which she was the first author, in the top zoonotic disease, wildlife disease and veterinary pathology journals.

 

Dr. Rothenburger’s research has taken an ecological approach to understanding factors associated with pathogen carriage in Norway rats, a neglected species of global public health significance. This pioneering work led to 4 peer-reviewed, 1st author papers and 6 presentations during her PhD studies and was recognized by the Governor General’s Academic Gold Medal and the Forester Medal, the two most prestigious PhD student awards at the University of Guelph. In related work, she conducted one of the largest pathology studies in any wild terrestrial mammalian species. Using > 600 wild rats, her studies have substantially advanced the knowledge of diseases in wild rats, including the discovery of heart and respiratory diseases, resulting in 6 peer-reviewed papers. These results establish the baseline of expected lesions in wild rats, which will help urban rat researchers, public health officials and pest controllers understand how disease impacts rat ecology to better mitigate the risk to human health and better manage urban rat populations.

 

As a wildlife disease expert, she engages in wildlife disease discovery research. For instance, in 2017 she discovered the first outbreak of epizootic hemorrhagic disease (EHD) in deer in Ontario, which is an important geographical range expansion that may be driven by climate change. In general, these disease discovery efforts advance fundamental knowledge about wildlife diseases, and are directly useful to wildlife biologists, veterinarians and disease ecologists.

, • Research

New study: sick rats may pose greater risk to human health


The sicker a rat is, the more likely it is to carry bacteria that can cause disease in people. That’s the conclusion of my recent study.   Wild urban rats carry a number of bacteria that can cause disease in…

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Peer Reviewed Papers

Case JE, Pederzolli RLA, Clark EG, Fenton H, Kutz SJ, Grahn BH, Rothenburger JL. 2022. Congenital cataract and spherophakia leading to starvation in a free-ranging muskox neonate from the Northwest Territories, Canada. Journal of Veterinary Diagnostic Investigation. 34(1):160-163.

Fenton H, Cluff DH, Blakley B, Rothenburger JL. 2022. Hepatic fibrosis and mineralization associated with deficient vitamin E in a free-ranging barren-ground caribou (Rangifer tarandus groenlandicus) from the Northwest Territories. Canadian Veterinary Journal. 63(2):157-160.

Greenfield JB, Anderson MV, Dorey EA, Redman E, Gilleard JS, Nemeth NM, Rothenburger JL. Molecular characterization of Sarcocystis canis as a cause of protozoal encephalitis in a free-ranging black bear (Ursus americanus). Journal of Veterinary Diagnostic Investigation. 34(1):146-15

Rothenburger JL, Di Francesco J, Leclerc LM, van der Meer F, Tomaselli M, Zabek E, Kutz SJ. 2021. Corynebacterium freneyi bacterial septicemia secondary to contagious ecthyma in a wild muskox (Ovibos moschatus). Journal of Wildlife Diseases. 57(1):225-229.

Fisher M, Harrison TMR, Nebroski M, Kruzkiewicz P, Rothenburger JL, Ambagala A, Macbeth B, Lung O. 2020. Discovery and comparative genomic analysis of elk circovirus (ElkCV), a novel circovirus species and the first reported from a cervid host. Nature Scientific Reports. 10(1):19548.

Chappell B, Frayne KMF, Davies JL, Macbeth BJ, Ngeleka M, Rothenburger JL. Lesions of Mycobacterium avium spp. hominissuis infection resembling M. bovis lesions in a wild mule deer, Canada. Emerging Infectious Diseases. 26(7):1614-1616.

Ma L, Chen Z, Huang DW, Cisse O, Rothenburger JL, et al. 2020. Diversity and complexity of the large surface protein family in the compacted genomes of various Pneumocystis mBio. 11(2). pil e02878-19.

Rothenburger JL, Himsworth CG, Nemeth N, Pearl DL, Jardine CM. The devil is in the details—host disease and co-infections associated with zoonotic pathogen carriage in Norway rats (Rattus norvegicus). Zoonoses and Public Health. 66:622-635. doi: https://doi.org/10.1111/zph.12615

Rothenburger JL, Himsworth CG, Nemeth N, Treuting PM, Jardine CM. Pathology of wild Norway rats in Vancouver, Canada. Journal of Veterinary Diagnostic Investigation. 31(2):184-199. doi: 10.1177/1040638719833436.

Rothenburger JL. Tracheobronchopathia osteochondroplastica: a rare tracheal lesion in a free-ranging grizzly bear (Ursus arctos). Journal of Veterinary Diagnostic Investigation. 31:608 –610. doi: 10.1177/1040638719844553

Allen SE, Rothenburger JL, Jardine CM, Rudder M, Ambagala A, Hooper-McGrevy K, Turukawa-Stoffer T, Nemeth NM. 2019. Epizootic hemorrhagic disease virus in white-tailed deer, Canada. Emerging Infectious Diseases. 25(4):832-834. doi: 10.3201/eid2504.180743

Rothenburger JL, Himsworth CG, Nemeth NM, Pearl DL, Jardine CM. 2018. Environmental factors associated with the carriage of bacterial pathogens in Norway rats. EcoHealth. 15(1):82-95. doi: 10.1007/s10393-018-1313-x

Rothenburger JL, Rouseau J, Weese JS, Jardine CM. 2018. Livestock-associated Methicillin-resistant Staphylococcus aureus and Clostridium difficile in wild Norway rats (Rattus norvegicus) from Ontario swine farms. Canadian Journal of Veterinary Research. 82(1):66-69.

Rothenburger JL, Himsworth CG, Nemeth NM, Pearl DL, Jardine CM. 2018. Beyond abundance: how microenvironmental features and weather influence Bartonella tribocorum prevalence in urban Norway rats (Rattus norvegicus). Zoonoses and Public Health. 65(3):339-351. doi: 10.1111/zph.12440

Rothenburger JL, Himsworth CG, Nemeth NM, Pearl DL, Jardine CM. 2017. Environmental factors and zoonotic pathogen ecology in urban exploiter species. EcoHealth. 14(3):630-641. doi: 10.1007/s10393-017-1258-5

Rothenburger JL, Hartnett EA, James F, Grahn BH. 2017. Anophthalmia in a wild Eastern gray squirrel (Sciurus carolinensis). Journal of Wildlife Diseases. 53(4):942-945. doi: 10.7589/2017-02-048

Rothenburger JL, Hoberg E, Wagner B. 2016. First report of Protechinostoma mucronisertulatum (Echinostomatidae) in a Sandhill Crane (Grus canadensis) from Saskatchewan, Canada. Comparative Parasitology. 83(1):111-116. doi: 10.1654/1525-2647-83.1.111

Rothenburger JL, Myers S, Lockerbie B, Wobeser B. 2016. Novel papillomaviral sequences detected within epidermal plaques in a wolf (Canis lupus). Journal of Wildlife Diseases. 52(1):177-9. doi: 10.7589/2015-04-102

Tourigny E, Thomas R, Guiry E, Earp R, Allen A, Rothenburger JL, Lawler D, Nussbaumer M. 2016. An osteobiography of a 19th-century dog from Toronto, Canada. International Journal of Osteoarchaeology. 26:818–829. doi: 10.1002/oa.2483

Rothenburger JL, Himsworth CG, Clifford CB, Ellis J, Treuting PM, Leighton FA. 2015. Respiratory pathology and pathogens in wild urban rats (Rattus norvegicus and Rattus rattus). Veterinary Pathology. 52(6):1210-1219. doi: 10.1177/0300985815593123

Rothenburger JL, Bennett KR, Bryan L, Bollinger TK. 2015. Septicemic listeriosis in wild hares from Saskatchewan, Canada. Journal of Wildlife Diseases. 51(2):503-508. doi: 10.7589/2014-06-159

Rothenburger JL, Himsworth CG, Treuting PM, Leighton FA. 2015. Survey of cardiovascular pathology in wild urban Rattus norvegicus and Rattus rattus. Veterinary Pathology. 52(1):201-208. doi: 10.1177/0300985814528220

Rothenburger JL, Himsworth CG, Lejune M, Treuting PM, Leighton FA. 2014. Lesions associated with Eucoleus sp. in the non-glandular stomach of wild urban rats (Rattus norvegicus). International Journal for Parasitology: Parasites and Wildlife. 3:95-101. doi: 10.1016/j.ijppaw.2014.04.003

Rothenburger JL, Himsworth CG, Chang V, Lejune M, Leighton FA. 2014. Capillaria hepatica in wild Norway Rats (Rattus norvegicus) from Vancouver, Canada. Journal of Wildlife Diseases. 50(3):628-633. doi: 10.7589/2013-09-256

Anholt H, Himsworth CG, Rothenburger J, Proctor H, Patrick DM. 2014. Ear mange mites (Notoedres muris) in black and Norway rats (Rattus rattus and Rattus norvegicus) from inner-city Vancouver, Canada. Journal of Wildlife Diseases. 50(1):104-108. doi: 10.7589/2013-02-046

Taketeloff N, Manning ST, Weese JS, Campbell J, Rothenburger J, Stephen C, Bastura V, Gow SP, Reid-Smith R.  2009. Prevalence of Methicillin-resistant Staphylococcus aureus colonization in horses in Saskatchewan, Alberta, and British Columbia. Canadian Veterinary Journal 50(11):1177-1180.

Non-Peer-Reviewed Academic Papers, Reports and Textbook Chapters

Caswell JL, Bassel LL, Rothenburger JL, Gröne A, Sargeant JM, Beck AP, Ekman S, Gibson-Corley KN, Kuiken T, LaDouceur EEB, Meyerholz DK, Origgi FC, Posthaus H, Priestnall SL, Ressel L, Sharkey L, Teixeira LBC, Ward JM, Webster JD, Yamate J. 2018. Observational study design in veterinary pathology. Part 1: study design. Veterinary Pathology. 55(5):607-621. doi: 10.1177/0300985818785705

Caswell JL, Bassel LL, Rothenburger JL, Gröne A, Sargeant JM, Beck AP, Ekman S, Gibson-Corley KN, Kuiken T, LaDouceur EEB, Meyerholz DK, Origgi FC, Posthaus H, Priestnall SL, Ressel L, Sharkey L, Teixeira LBC, Ward JM, Webster JD, Yamate J. 2018. Observational study design in veterinary pathology. Part 2: methodology and validation of methods. Veterinary Pathology. 55(6):774-785. doi: 10.1177/0300985818798121

Delaney MA, Treuting PM, Rothenburger JL. 2018. Chapter 19 Lagomorpha. In: McAloose M, Terio K, St Leger J (Eds). Pathology of Wildlife and Zoo Animals. Elsevier.

Delaney MA, Treuting PM, Rothenburger JL. 2018. Chapter 20 Rodentia. In: McAloose M, Terio K, St Leger J (Eds). Pathology of Wildlife and Zoo Animals. Elsevier.

Agnew DW, Nofs S, Delaney MA, Rothenburger JL. 2018. Chapter 21 Xenartha, Erinacoemorpha, Some Afrotheria, and Phloidota. In: McAloose M, Terio K, St Leger J (Eds). Pathology of Wildlife and Zoo Animals. Elsevier.

Rothenburger T, Rothenburger JL. 2015. First observation of a brown thrasher nest (Toxostoma rufum) on stationary farm equipment. Bluejay. 73(4):184-185.

Rothenburger JL, Leighton FA. 2012. Disease risk assessment for the reintroduction of plains bison into Banff National Park. Prepared for Parks Canada and the Canadian Wildlife Health Cooperative.